ContentsPage 14 -What are biomolecular condensates, and will they be a breakthrough in diabetes treatment?Ameet Nathwani at Dewpoint Therapeutics considers the use of biomolecular condensates as a potential treatment optionPage 16 -Alzheimer’s disease and age-related macular degeneration – how are they linked and what are the treatments?Alexander Gebauer from Galimedix Therapeutics explains the link between AD and AMD and how treatment for both could develop in the futurePage 18 -The impact of the cost of living crisis on healthBetsy Goodfellow from Pharmafocus considers the impact of the ongoing cost of living crisis and why this is so significant in terms of healthTop NewsPage 4Report finds NHS may miss out on new drugs due to rising costsPage 6AstraZeneca announces positive results from phase 3 trial for Tagrisso plus chemotherapyPage 7– SNIPR Biome reports positive findings for first-in-human, CRISPR-based microbial gene therapyPage 8FDA approves Pfizer’s RSV vaccine for older adultsPage 10Scientists at MIT and McMaster University use AI to find new antibiotic to fight superbugPage 12Astellas and Sony enter collaborative research agreementOur TeamExecutive Director
PMGroup Worldwide Ltd
Karl Equi
Group Managing Editor
Iona Everson
ieverson@pmlive.comEditorial Assistants
Betsy Goodfellow

James Spargo
Sales Manager
Eliot Haynes
eliot@pharmafile.comDesign & Layout
Peter May
Pharmafocus is published by:Samedan Ltd
Suite E, 11 Bell Yard Mews,
175 Bermondsey Street,
London, SE1 3TN
Tel: +44 (0)20 7724 3456
Fax: +44 (0)20 7403 7747
www.pharmafile.comSubscriptions & Data ManagementCurwood CMS Tel: 01580 883840enquiries@c-cms.comISSN: 1465-5403
Pharmafocus is sent free of charge to selected permanent employees of ethical and OTC pharmaceutical and biotech companies. Employees are specifiers from middle and senior management with responsibility for making buying decisions. Selection is at the discretion of the Publisher. Copies are also available on a subscription basis at an annual fee of £115 (UK), £145 (Europe) and £185 (RoW).All subscriptions payable to Samedan. Back copies can be purchased for £15.00 each. Pharmafocus is published by Samedan Ltd. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form without permission, unless for the purposes of reference and comment.©2023 Samedan Ltd, Pharmaceutical PublishersThe opinions and views expressed by contributors to this publication are not necessarily those of the Editor or the Publisher and, while every care has been taken in the preparation of the newspaper, the Editor and the Publisher are not responsible for such opinions and views, or for any inaccuracies in the articles. The Publisher is not responsible for any images supplied by contributors. While every care is taken with artwork supplied, the Publisher cannot be held responsible for any loss or damage incurred. The entire content of this publication is protected by copyright. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form, by any means – electronic, mechanical, photocopying or otherwise – without the prior permission of the Publisher.