Issue Cover

Clinical Trials

Latest updates on clinical trials and their results.

Articles

article-item
TauRx builds on its Alzheimer’s momentum after tablet found to slow progression of the disease

After TauRx Pharmaceutics’ investigational Alzheimer’s treatment hydromethylthionine mesylate (HMTM) was found to slow the disease’s progression it could, if approved, become the first oral treatment targeting the tau protein.

28 April 2025Clinical Trials
article-item
Novo’s Rybelsus found to reduce major adverse cardiovascular events

Novo Nordisk’s diabetes treatment Rybelsus (semaglutide) has been found to significantly reduce the risk of major adverse cardiovascular events (MACE).

28 April 2025Clinical Trials
article-item
Johnson & Johnson’s Darzalex gains boost over conventional chemotherapy

Johnson & Johnson’s Darzalex (daratumumab) could help patients with newly diagnosed multiple myeloma (NDMM) approach normal life expectancy without their disease progressing.

28 April 2025Clinical Trials
article-item
Potential rare eye disease treatment sees phase 1 success

Indian biotechnology company Eyestem Research has achieved successful results from a phase 1 trial of Eyecyte-RPE, its potential therapy for a rare, advanced form of dry age-related macular degeneration (AMD).

28 April 2025Clinical Trials
article-item
Corcept’s relacorilant improves ovarian cancer survival in phase 3 trial

Corcept Therapeutics’ oral ovarian cancer drug relacorilant has improved progression-free survival in the ROSELLA trial.

28 April 2025Clinical Trials
article-item
Recce Pharmaceuticals reports positive phase 2 data for skin infection drug

Recce Pharmaceuticals has announced positive patient data from its phase 2 clinical trial into RECCE 327 (R327), for the treatment of acute bacterial skin and skin structure infections (ABSSSIs), including diabetic foot infections (DFI).

13 March 2025Clinical Trials
article-item
Emalex Bioscience’s candidate for Tourette syndrome meets phase 3 endpoints

Paragon Bioscience’s clinical biopharma spin-out, Emalex Bioscience, has announced that its lead candidate for the treatment of Tourette syndrome has met its primary and secondary endpoints in a recent phase 3 study.

13 March 2025Clinical Trials
article-item
PulseSight Therapeutics closes Series A financing for dry AMD phase 1 clinical study

Ophthalmology biotech PulseSight Therapeutics has confirmed the closure of its Series A funding round, the proceeds of which will be used to fund a phase 1 study into its dry age-related macular degeneration (AMD) therapy, PST-611. The funding round was supported by existing investor Pureos BioVentures.

13 March 2025Clinical Trials
article-item
Data shows long-term success for biosimilar switch in IBD

Real-world data into a mandatory non-medical switching policy for patients with inflammatory bowel disease (IBD) has shown long-term safety and efficacy. The patients transitioned from using adalimumab (Humira) to a biosimilar due to the enaction of the policy in British Columbia, Canada – the first Canadian province to do so.

13 March 2025Clinical Trials
article-item
€7m financing announced to further clinical trials in thrombo-inflammatory diseases

Aplagon, a clinical stage biopharmaceutical company dedicated to the development of first-in-class therapeutics for thrombo-inflammatory diseases, has announced the closing of a €7m financing round for the initiation of phase 2a of its clinical trials.

12 February 2025Clinical Trials
article-item
AnaCardio raises $19m in funding round for heart failure candidate

Swedish biopharmaceutical company AnaCardio has announced the completion of a Series A extension financing round that has raised $19m for its novel contractile agents. The round was co-led by Novo Holdings, Pureos Bioventures and Sound Bioventures.

12 February 2025Clinical Trials
article-item
Positive topline results announced in phase 2 alcohol use disorder study

Beckley Psytech Ltd, a clinical-stage biopharmaceutical company that specialises in the production of accessible medicines for mental health conditions, has announced positive results for the phase 2a study into BPL-003 in patients with moderate-to-severe alcohol use disorder (AUD).

12 February 2025Clinical Trials