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Contents
Page 14 - The climate crisis: what is it and is pharma to blame?
Stefan Woxström at AstraZeneca tells
Pharmafocus
about the link between climate change and human health
Page 16 - Why modelling patient heterogeneity is crucial in drug development
Prof Shai Shen-Orr at CytoReason explores the need for patient heterogeneity and why this is so central to successful drug development
Page 18 - How regulators are keeping pace with technology
Fiona Maini from Medidata speaks about pharmaceutical regulation and the opportunities and challenges of digitalisation and a rapidly evolving industry
Page 20 - Could climate change along with pandemics equal a recipe for disaster?
Betsy Goodfellow considers the effects of climate change and how this could worsen, or even trigger, future pandemics
Top News
Page 4
– FDA issues update around changes to COVID-19 vaccines’ EUAs
Page 6
– Eli Lilly shares positive results from phase 3 study of donanemab for early Alzheimer’s disease
Page 7
– Merck’s relapsing multiple sclerosis trial put on FDA partial clinical hold over liver injuries
Page 9
– NICE recommends two CAR T treatments for blood cancers to the Cancer Drugs Fund
Page 10
– 3B Pharmaceuticals and Novartis enter into licensing agreement for FAP-targeting technology
Our Team
Executive Director
PMGroup Worldwide Ltd
Karl Equi
Group Managing Editor
Iona Everson
ieverson@pmlive.com
Editorial Assistants
Betsy Goodfellow
betsy@pharmafile.com
James Spargo
james@samedanltd.com
Sales Manager
Eliot Haynes
eliot@pharmafile.com
Design & Layout
Peter May
designer@samedanltd.com
Pharmafocus
is published by:
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ISSN: 1465-5403
Pharmafocus
is sent free of charge to selected permanent employees of ethical and OTC pharmaceutical and biotech companies. Employees are specifiers from middle and senior management with responsibility for making buying decisions. Selection is at the discretion of the Publisher. Copies are also available on a subscription basis at an annual fee of £115 (UK), £145 (Europe) and £185 (RoW).
All subscriptions payable to Samedan. Back copies can be purchased for £15.00 each. Pharmafocus is published by Samedan Ltd. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form without permission, unless for the purposes of reference and comment.
©2023 Samedan Ltd, Pharmaceutical Publishers
The opinions and views expressed by contributors to this publication are not necessarily those of the Editor or the Publisher and, while every care has been taken in the preparation of the newspaper, the Editor and the Publisher are not responsible for such opinions and views, or for any inaccuracies in the articles. The Publisher is not responsible for any images supplied by contributors. While every care is taken with artwork supplied, the Publisher cannot be held responsible for any loss or damage incurred. The entire content of this publication is protected by copyright. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form, by any means – electronic, mechanical, photocopying or otherwise – without the prior permission of the Publisher.
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